The metabolic syndrome

The metabolic syndrome is a combination of medical disorders that increases the risk of cardiovascular disorders and is highly correlated to obesity and more specifically central obesity. This condition is the outcome of a self-destructive lifestyle.

Since the dramatic rise in obesity, the metabolic syndrome has been studied a lot and is referred to by the medical profession as the « silent killer ». A sedentary lifestyle coupled with a high calorie intake results in a positive energy balance: too much supply and not enough consumption. This is the case for a growing number of people. The consequence is the metabolic syndrome, a factor in cardiovascular illnesses. It is nowadays essential to detect it among people who are overweight, obese, who have diabetes type 2, etc.…

15 to 25 % of the occidental population suffers from the metabolic syndrome. The risk factor of dying due to cardiovascular conditions is twice or four times higher than average. The risk of suffering from diabetes type II is also higher, 5 to 9 times higher than average.

In 2025, an estimated 2 out of every 3 Europeans will be obese!!!

1. Definition

- Insulin resistance
A fasting insulin of >= 6.1 mmol/l or >= 110 mg/dl

- Central obesity
Waist circumference for women > 80 cm
Waist circumference for men > 94 cm

- High levels of triglycerides
>= 1,7 mmol/l or >= 150 mg/dl

- Low levels of HDL
Women < 1,3 mmol/l or > 50 mg/dl
Men < 1 mmol/l or < 40 mg/dl

- High blood pressure
>= 130/85 mm Hg

The culprits:
- intake of exaggerated amounts of simple carbohydrates (x3)
- excessive intake of saturated fat
- sedentary lifestyle
- nutriment deficiency: magnesium, zinc, oméga-3, fibers, vitB6.

2. Causes and consequences

Eating reat amounts carbohydrates and saturated fatty acids
| 1
Increase of the fat tissue
| 2
Oxidation
| 3
Inflammation
_________________|__________________
| 4
| 5
| 6
Deregulation of the glucose levels
Dyslipidemia
Deregulation of neurotransmitters

1. The intake of simple carbohydrates and saturated fatty acids results in the increase of fat tissue. The intake of large quantities of simple carbohydrates (on average 3 times the recommended daily amounts) and saturated fatty acids are the causes of obesity and metabolic syndrome.

2. The increase of fat mass (especially fat tissue around the liver, the heart...) leads to oxidation.

3. Oxidation leads to an inflammation (which triggers the activation of the NF Kappa B signal which in turn leads to the secretion of inflammatory adipokines).

4. The oxidation and inflammation lead to a deregulation of the glucose levels, intolerance to glucose followed by insulin resistance.

5. Cardiovascular problems are linked to inflammation due to oxidation. This leads to dyslipidemia and high blood pressure, often followed by myocardial infarction (heart attack).

6. A lower level of serotonin is also a consequence of inflammation and oxidation. Serotonin is produced from tryptophane. If there is enough tryptophane, serotonin will increase.

A lack of serotonin induces sugar cravings, aggressiveness, suicidal thoughts, depression, mood swings…

3. Conclusions

We are now aware of the real danger the metabolic syndrome poses, which is why we systematically measure the waist circumference. The studies have shown that high waist circumference linked to hypertriglyceridemia increases by 80% the risk of metabolic dysfunction.

It is important to detect the metabolic syndrome among those people who show no symptoms. It can thus be treated in time, not only by normalizing the sugar rates but also by eliminating the risk of developing abdominal fat.

4. Target

Just losing a few kilos is enough

Many studies show that a slight weight loss of roughly 10% can lead to very favorable metabolic and cardiovascular results. The unhealthy fat, i.e. abdominal fat, melts first, long before the subcutaneous fat. A 10% weight loss is equivalent to losing 30% of fat tissue.




 
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